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Jay Sarthy, MD, PHD
Investigador principal
El Dr. Sarthy es médico tratante en la unidad de trasplante de médula ósea del Seattle Children's. También continuó su investigación en biología básica en Seattle Children's, centrándose en la epigenética de los cánceres pediátricos e identificando tratamientos contra el cáncer pediátrico menos tóxicos. En su tiempo libre, el Dr. Sarthy disfruta pasar tiempo con su familia. También le gusta el senderismo, el esquí, el kayak y escuchar música country clásica.
Stephanie Namciu PhD
Científico investigador III
Stephanie recibió su B.S. en Nutrición Animal y M.S. en Fisiología Aviar de la Universidad Estatal de Ohio y su Ph.D. en Biología Molecular de la Facultad de Medicina de la Universidad de Cincinnati. Su trabajo de posgrado se centró en el papel del oncogén nuclear, c-ski, en el desarrollo y diferenciación hematopoyética. Su trabajo postdoctoral posterior en el Centro Oncológico Fred Hutchinson se centró en el papel de la cromatina en la regulación de la expresión genética. Como científica del personal de Fred Hutchinson, su investigación se centró en los mecanismos de formación de translocaciones cromosómicas recíprocas en las leucemias. Luego, Stephanie se mudó al Instituto de Investigación del Noroeste del Pacífico para continuar su investigación sobre la regulación genética. y reordenamientos cromosómicos, centrándose en las topoisomerasas de tipo II.
Morgan Merril
Científico investigador II
Morgan estudió el desarrollo de la retina durante su programa universitario. Después de mudarse a Seattle, se unió al laboratorio de Jim Olson, donde su trabajo se centró en la terapia con proteínas en tumores cerebrales. A Morgan le apasiona hacer ciencia rigurosa que proporcione una columna vertebral sólida para los agentes terapéuticos que se presenten en ensayos clínicos. A Morgan le encantan los juegos de todo tipo, desde cartas hasta ordenadores. Leyó historias sobre exploración espacial y superación de dragones. Pasa su tiempo libre haciendo cosas, ya sea horneando o haciendo nudos en hilo.
Chao-Jen Wong, PhD
Bioinformatics Research Associate III
Chao-Jen received her B.A. from California State University, Fullerton and Ph.D. in Applied Mathematics from Claremont Graduate University. She began her career in genomic science at Fred Hutchinson and joined Sarthy Lab in late October 2023. Her prior work experience included building infrastructure for Bioconductor Core, conducting computational research on Facioscapulohumeral Muscular Dystrophy (FSHD), and developing software. She enjoys coding and solving mathematical problems on paper. Her other interests include rowing, biking, bodyweight training, and walking her dog and children.
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Gabe Boyle, PhD
Postdoctoral Fellow
Gabe received his B.S. in Neuroscience from Ohio State University in 2016 and his PhD in Molecular and Cellular Biology from University of Washington in 2023. His doctoral research in Dr. Doug Fowler's lab focused on understanding heterogeneous drug response amongst people and between cell subpopulations. In his current role, he is interested in employing high throughput methods in genomics, epigenomics, and proteomics to study how chemotherapeutics kill cancer cells. By broadening our understanding of drug activity, both anti-cancer and off-target, we can make sure patients are receiving the best treatments for their particular biology. In his free time, Gabe enjoys Brazilian Jiu Jitsu, physical therapy to recover from Brazilian Jiu Jitsu injuries, and searching for Mothman with his World of Warcraft guild Mothman Search Team.
Carter Zivin
Undergraduate Research Intern
Carter is an undergraduate studying biology at Carnegie Mellon University. While at school she is a mechanic for APEX buggy racing. Carter is originally from Seattle and at home enjoys biking, listening to jazz music, and walking with her dog Puff.
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Miembro más nuevo del equipo
¡Siempre estamos buscando científicos talentosos y apasionados para unirse a nuestro laboratorio! Consulte nuestro ofertas de trabajo actuales o Contáctenos para solicitar información sobre puestos vacantes para técnicos, estudiantes de posgrado y posdoctorados.
Clara Libbrecht, MD, PhD
Fellow-MD
Clara is a pediatric hematologist/oncologist at Seattle Children’s Hospital. Working with Dr. Jay Sarthy and Dr. Mignon Lee-Cheun Loh, her research focuses on epigenetic regulation of mixed phenotypic acute leukemia.
Malcolm T.S. Mallard
Guardián de laboratorio
Malcolm Tape Station Mallard, often known as Malcolm T.S., is the steadfast guardian of the Sarthy Lab. His story begins on the serene shores of Lake Washington, where he was hatched among a brood of ordinary mallards. An adventurous duck, one day he found himself 1.3 miles away from his nest. While finding his way out of the dark shadow of trees, he sensed a pair of big, shinny eyes glaring at him through a bush—it was a raccoon waiting to strike. At that perilous moment, he encountered Dr. Sarthy, who was hiking at the time. He saved Malcolm from the jaws of the predator. Thereafter, he followed Jay to the lab and took on the role of protector, patrolling the lab bays and safeguarding groundbreaking discoveries.
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Former Members
Samantha Kaonis PhD
Research Scientist II
Samantha received her B.S. in Bioengineering from Washington State University in 2018 and her PhD in Biomedical Engineering from Colorado State University in 2022. Her doctoral research in Dr. Soham Ghosh's lab focused on MSC mechanobiology and epigenetics. In her current role, Samantha is particularly interested in the chromatin biology of pediatric cancers and the associated bioinformatics. Outside of work, Samantha enjoys birdwatching, cooking, and walking her dogs.
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Carli Newman
Research Technician II
Carli is a recent graduate of Reed College where she received her B.A. in Biochemistry and Molecular Biology. Her scientific interests are broad and she enjoys working at the intersection of multiple fields including biology, computer science, chemistry, and math. Carli is originally from Whidbey Island where she was first introduced to many of her hobbies including kayaking, playing ultimate frisbee, camping, reading, and music.
Stephanie Namciu PhD
Research Scientist III
Stephanie received her B.S. in Animal Nutrition and M.S. in Avian Physiology from the Ohio State University, and her Ph.D. in Molecular Biology from the University of Cincinnati College of Medicine. Her graduate work focused on the role of the nuclear oncogene, c-ski, in hematopoietic development and differentiation. Her subsequent postdoctoral work at Fred Hutchinson Cancer Center focused on chromatin’s role in the regulation of gene expression. As a Staff Scientist at Fred Hutchinson her research focused on mechanisms of reciprocal chromosomal translocation formation in leukemias. Stephanie then moved to the Pacific Northwest Research Institute to continue her research on gene regulation and chromosome rearrangements, focusing on Type II Topoisomerases.
